Topical analgesics and kinesiology taping techniques are routinely used by patients for pain control and function. Understanding the pharmacology and clinical application of common OTC and prescription topical analgesics will enable the clinician to advise patients on their appropriate use. Since taping is often used in conjunction with topicals analgesics, and the research continues to evolve on the mechanism of action of kinesiology sports tape. Learn the facts on taping and topicals to better advise patients on their use and potential complications.