Inflammation is a coordinated process induced by microbial infection or tissue injury. The process involves a vibrant immune response which if not adequate can lead to damage and destruction of tissues, multiple organ failure, and even death. The main function of inflammation is then its resolution along with tissue repair and a return to a state of homeostasis. Vital to this process is the efficacy of such a system to mount a rapid response appropriate to the inflammation while limiting the damaging aspects of as much as possible. Thus, the ideal inflammatory response is rapid and destructive (when necessary), yet specific and self-limiting.